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Porcupine-IN-1 is as potent as the clinical compound LGK974 in a cell based STF reporter gene assay
BAY-1142524
4-dihydroxy-5-(10-methylundecanamido)oxane-2-carboxylic acid
and pruritus
Smiles: COC1C=C(C=C(OC)C=1OC)NC1=NC2=C(C=N1)C=CN2C1=CC(CCC#N)=CC=C1
1, 2, 3, 4, 5, 6-Hexabromocyclohexane 13462 Porcupine-IN-1 is as potent as1,2,3,4,5,6 Hexabromocyclohexane (NSC7908) is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation with IC50 value to be estimated in low micromolar range. Product information CAS Number: 1837 91 8 Molecular Weight: 557. 54 Formula: C6H6Br6 Chemical Name: 1,2,3,4,5,6 hexabromocyclohexane Smiles: BrC1C(Br)C(Br)C(Br)C(Br)C1Br InChiKey: QFQZKISCBJKVHI UHFFFAOYSA N InChi: InChI=1S C6H6Br6 c7 1 2(8)4(10)6(12)5(11)3(1)9 h1 6H Technical Data
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